Overview
BIJUTOX® 100 U is a high-purity injectable formulation of Clostridium botulinum toxin type A, engineered to soften dynamic facial lines and wrinkles. Rigorous activity testing (87–125%) ensures reliable performance and consistent clinical outcomes.
Composition
- Active Ingredient: Clostridium botulinum toxin type A (100 U)
- Excipients: Human serum albumin (0.5 mg), sodium chloride (0.9 mg)
Appearance & Reconstitution
Supplied as a white- to pale-yellow lyophilisate in a clear vial. Reconstitute with sterile, preservative-free 0.9% sodium chloride:
- Draw up the appropriate volume of saline.
- Inject slowly into the vial to avoid foam formation.
- Gently swirl until dissolved—do not shake.
- Label with the date and time of dilution; use within 24 hours.
Indications
- Moderate to severe glabellar (frown) lines
- Forehead transverse lines
- Crow’s feet
- Marionette and platysmal bands
- Mouth corner lift and masseter hypertrophy
- Platysmal and trapezius muscle lines
Dosage & Administration
Administer intramuscularly using a 30 G needle. Tailor injection sites and volumes to the treatment area, following established protocols for glabellar and periorbital lines.
Efficacy
Patients typically notice improvement within 3–7 days. Cosmetic effects persist for 7–9 months, with retreatment intervals individualized based on muscle activity and patient preference.
Storage & Handling
- Unopened vials: Refrigerate at 2–8 °C; do not freeze.
- Shelf life: 36 months from manufacture.
- Reconstituted solution: Store at 2–8 °C and discard after 24 hours.
Safety & Precautions
Intended for use by trained healthcare professionals only. Inspect reconstituted solution for clarity and absence of particulates before injection. Common adverse reactions include injection-site discomfort and transient muscle weakness. Serious effects (e.g., dysphagia, respiratory difficulty) are rare but require prompt attention. Continuous cold-chain maintenance is essential to preserve potency.
