ONETOX 100U

Product Profile

• Active Ingredient: 100 U Clostridium botulinum toxin type A per vial
• Excipients: Human serum albumin (0.5 mg), sodium chloride (0.9 mg)
• Presentation: Lyophilized white-to-light yellow powder in a clear vial
• Reconstitution: Add sterile, preservative-free 0.9 % saline; swirl gently; use within 24 hours
• Storage: Refrigerate at 2–8 °C; do not freeze

Mechanism of Action

ONE TOX® temporarily blocks acetylcholine release at neuromuscular junctions, producing localized muscle relaxation. In aesthetic treatments, this softens expression lines; in therapeutic settings, it reduces muscle spasms.

Indications

Aesthetic Uses

• Glabellar (frown) lines
• Forehead wrinkles
• Crow’s feet
• Perioral lines
• Masseter contouring
• Eyebrow lifting
• Platysmal band smoothing

Therapeutic Uses

• Hyperhidrosis (excessive sweating)
• Bruxism (teeth grinding)
• Muscle spasticity (e.g., cerebral palsy)
• Blepharospasm
• Off-label: chronic migraine relief

Dosing & Administration

• Reconstitution Ratios:
  • 1 mL saline → 100 U/mL
  • 2 mL saline → 50 U/mL
• Injection: Administer intramuscularly according to clinical guidelines, adjusting dose by treatment area.
• Onset: 2–5 days
• Duration: 4–6 months (varies by individual and site)

Safety & Precautions

• Administer only by trained professionals.
• Common reactions: injection-site pain, swelling, bruising, headache, transient ptosis or localized weakness.
• Rare but serious: dysphagia, respiratory compromise—monitor high-risk patients.

Shelf Life

Three years from manufacture. Maintain continuous cold-chain refrigeration to preserve potency.