NEURAMIS VOLUME

Formulation

• HA Concentration: 24 mg/mL
• Lidocaine: 0.3% for patient comfort
• pH Buffer: Physiological phosphate

Product Variants & Indications

1. NEURAMIS™ (Superficial Lines)

   • Particle Size: Smallest
   • Injection Depth: Superficial dermis
   • Uses: Very fine wrinkles—worry lines, periorbital and perioral lines

2. NEURAMIS™ Deep (Moderate Wrinkles)

   • Particle Size: Medium
   • Injection Depth: Mid-dermis
   • Uses: Moderate lines—glabellar folds, oral commissures, lip contour

3. NEURAMIS™ Volume (Deep Folds & Contours)

   • Particle Size: Largest
   • Injection Depth: Deep dermis or superficial subcutis
   • Uses: Deep folds—nasolabial and marionette lines; lip plumping; cheek and chin contouring

Areas of Treatment

• Cheeks & cheekbones
• Chin enhancement
• Nasolabial folds & marionette lines
• Forehead and other fine wrinkles
• Lip contouring & plumping

Administration & Protocol

• Injection Depth: Mid to deep dermis (per variant)
• Technique: Linear thread or small bolus
• Treatment Interval: Every 3–6 months, per patient needs

Efficacy & Duration

• Onset: Immediate hydration and subtle lift
• Duration: 6–12 months (varies by product and patient factors)

Storage & Handling

• Temperature: 2–25 °C; avoid freezing, heat and direct sunlight
• Shelf Life: 24 months from manufacture
• Packaging: 1 mL prefilled syringe

Safety Profile

NEURAMIS™ is biocompatible and fully biodegradable. Lidocaine minimizes injection discomfort. Common, transient side effects may include redness, swelling or bruising. Administer only by qualified healthcare professionals.