LIPORASE
Liporase Hyaluronidase 1500 IU is a South Korean injectable enzyme preparation manufactured by Daehan Nupharm Co., Ltd. Each vial contains 1,500 International Units (IU) of hyaluronidase, an enzyme that breaks down hyaluronic acid (HA) and promotes its dispersion and absorption within tissues.
Hyaluronidase has established medical applications involving the dispersion of certain injected medicines and the reabsorption of excess tissue fluids. In aesthetic medicine, it is also used by qualified healthcare professionals for the correction of unwanted hyaluronic acid dermal fillers, where permitted under applicable regulations.
Supplied as a lyophilized powder, liporase comes in a box of 10 vials, providing a total of 15,000 IU of hyaluronidase.
Key Features
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Contains 1,500 IU of hyaluronidase per vial
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Enzyme that breaks down hyaluronic acid
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Used in clinical HA filler correction where permitted
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Established medical applications involving tissue permeability and fluid absorption
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Supplied as a freeze-dried powder for reconstitution
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Ten individually packaged vials per box
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Total enzyme activity of 15,000 IU per box
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Manufactured by Daehan Nupharm Co., Ltd.
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Made in South Korea
Applications & Indications
Liporase contains hyaluronidase, an enzyme with established medical uses and additional off-label applications in aesthetic medicine.
Manufacturer-Listed Medical Indications
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Increasing tissue permeability to facilitate the dispersion and absorption of certain injected medicines
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Supporting subcutaneous infusion and selected medical procedures
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Promoting the reabsorption of excess tissue fluids and blood
Off-Label Aesthetic Applications
Where permitted, qualified healthcare professionals may use hyaluronidase for:
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HA Filler Correction: Management of unwanted hyaluronic acid filler
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Excessive Filler Placement: Correction of overfilled areas
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Uneven Filler Distribution: Management of irregularities involving HA-based fillers
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Filler-Related Asymmetry: Correction of selected asymmetries associated with hyaluronic acid filler
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HA Filler Complications: Clinician-directed management of certain filler-related complications
Hyaluronidase is not a general-purpose filler dissolver. It does not directly dissolve non-HA fillers such as calcium hydroxylapatite, poly-L-lactic acid or polymethyl methacrylate.
Aesthetic filler dissolution should not be interpreted as an approved indication in every country.
Composition
Hyaluronidase – 1,500 IU per Vial
Hyaluronidase is an enzyme that catalyzes the breakdown of hyaluronic acid.
By degrading HA, it reduces the viscosity of hyaluronic acid-containing tissue components and facilitates their dispersion and absorption.
Formulation: Lyophilized powder for preparation according to the manufacturer's instructions.
The complete excipient composition should be confirmed against the original product insert supplied with the batch.
Product Specifications
Product Name: Liporase Injection
Product Category: Hyaluronidase Enzyme Preparation
Product Type: Injectable Lyophilized Powder
Active Ingredient: Hyaluronidase
Enzyme Activity: 1,500 IU per Vial
Packaging: 10 Vials per Box
Total Enzyme Activity: 15,000 IU per Box
Formulation: Freeze-Dried Powder for Reconstitution
Manufacturer: Daehan Nupharm Co., Ltd.
Country of Origin: South Korea
How Hyaluronidase Works
Hyaluronic acid is a naturally occurring component of connective tissue and the principal ingredient in many dermal fillers.
Hyaluronidase acts by breaking down hyaluronic acid, reducing its viscosity and facilitating its dispersion and absorption.
This mechanism explains its established role in certain medical applications and its use in aesthetic practice for managing unwanted HA filler.
The response to hyaluronidase can vary depending on the filler formulation, clinical circumstances, and individual patient factors. Its activity is not limited to injected filler and may also affect naturally occurring hyaluronic acid.
Hyaluronidase can cause hypersensitivity reactions, including serious allergic reactions. Appropriate clinical assessment and management are essential.
What's in the Box
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10 × Liporase Hyaluronidase vials (1,500 IU each)
Total Enzyme Activity: 15,000 IU
Storage & Handling
Store lipase according to the temperature and environmental conditions specified on the original manufacturer's packaging and accompanying instructions.
Keep unopened vials in their original packaging, protected from conditions that could compromise product stability.
Check the expiration date, batch number, and vial integrity before use.
Preparation, storage after reconstitution, and disposal must follow the manufacturer's current instructions and applicable medical standards.
Professional Use Only
This product is intended for qualified medical or aesthetic professionals and is not intended for self-administration.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
Intended Use
This product should be used only for its intended purpose and in accordance with the manufacturer’s product information.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
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Frequently asked questions
How much can I save with Brunodermafiller?
Brunodermafiller is committed to offering you the most competitive prices. Depending on the products and quantities you purchase, you can save up to 20% compared to other distributors.
How to pay for your order?
Due to the high-risk classification of injectable aesthetic products, many standard payment providers do not support transactions for these products. As a result, we do not accept card payments, Apple Pay, or PayPal. All payments are made via bank transfer only.
Here’s how it works: Once you place your order, you’ll receive bank transfer details based on the currency you choose sent securely via email within 24 hours. Please check your spam, junk, or promotions folder if you don’t see it. If it’s still missing, feel free to contact our support team and we’ll resend it promptly.
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Payment instructions are sent via email within 24 hours of placing your order. If you haven’t received them, please check your spam, junk, or promotions folder—it’s often filtered there. Still nothing? Contact our support team and we’ll make sure you get them right away.
Are there any additional custom charges?
In rare cases, depending on your country’s customs regulations and current events, additional custom fees might apply at delivery. These are unfortunately outside of our control and vary by region. Most of our customers don’t encounter extra charges, but if it does happen, we just want you to be aware of them in advance. If you refuse to pay and reject delivery, no refunds will be issued. We’re always here to help if anything comes up.
Are there any additional transfer fees?
In some cases, certain banks may charge a small fee for international payments. While this isn’t something we control (and we never add fees ourselves), we don’t want you to feel that cost is coming out of your own pocket. It also isn’t the quickest or most convenient,and while it’s not ideal, we really appreciate you going through it. That’s why we offer you a small gift upon reaching checkout. You’ll get to choose from a selection of free products to thank you for your order and make sure you’re still getting full value. It’s our way of showing you that your effort doesn’t go unnoticed.
How long does the shipping take?
- USA, Canada, Japan: 2–5 business days
- Europe (excluding Germany and Italy): 3–5 business days
- Germany & Italy: 3–6 business days (tracking available after about 5 working days)
- South Africa: 7+ business days
- Dominican Republic: 8–12 business days
Average worldwide delivery time is 3–5 business days. Delays may occur due to customs clearance or flight schedules.
How is my order packaged?
For aesthetic treatment products such as injectables, we use temperature-controlled packaging when required, following strict safety and hygiene standards. All parcels are shipped in discreet packaging by default. No product names or medical terms appear on the outside of the box.
How to modify or cancel my order?
To modify or cancel your order, please contact us as soon as possible at info@brunodermalfiller.com.If your order hasn’t been processed or shipped yet, we’ll do our best to accommodate your request. Once it’s been dispatched, changes or cancellations are no longer possible, but you may be eligible for a return or exchange after delivery
The product packaging looks different. Is it authentic?
Yes, in many cases this is completely normal. Manufacturers may update their packaging, labels, security features, or product design without changing the product itself.
Packaging, logos, colours, security seals, QR codes, and labels may vary between production batches. If you have any concerns, please contact our support team with your order number and clear photos of the product and packaging.
Which saline or lidocaine should I use with this product?
Please follow the manufacturer's instructions for the specific product you have purchased. Preparation requirements vary between products and manufacturers.
Always refer to the manufacturer's official instructions supplied with the product. Products should only be prepared and administered by appropriately qualified healthcare professionals in accordance with applicable local regulations.