EXO' ONE
EXO'ONE is a Korean exosome-based skin booster from JDBIO, developed for professional aesthetic skin care focused on hydration, skin texture, and visible signs of aging. Its two-component formulation combines a stem cell-derived exosome preparation with a separate hyaluronic acid (HA) solution.
According to JDBIO's published specifications, EXO'ONE contains 2 billion highly purified exosomes within a preparation reported to contain 6 billion extracellular vesicle particles. Exosomes are nanoscale extracellular vesicles involved in cellular communication and are being studied for their potential applications in skin care and aesthetic medicine.
Unlike conventional hyaluronic acid dermal fillers, EXO'ONE is positioned for overall skin-quality care rather than structural facial volumization. Each box contains one 50 mg Pure EXO vial and one 5 mL hyaluronic acid vial, supplied as a paired set.
Key Features
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Stem cell-derived exosome formulation
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Contains 2 billion highly purified exosomes, according to JDBIO
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Reported total of 6 billion extracellular vesicle particles
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Dual-component preparation with exosomes and hyaluronic acid
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Includes a 5 mL HA solution for moisture-focused skin care
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Developed for professional aesthetic skin-rejuvenation applications
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Focused on skin hydration, texture and elasticity
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Marketed for skin barrier care and improved complexion appearance
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Supplied as one paired set containing two vials
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Part of the JDBIO aesthetic product portfolio
Applications & Indications
EXO'ONE is marketed for professional cosmetic and aesthetic applications focused on improving the overall appearance and condition of the skin.
Its product positioning includes:
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Skin Hydration: Supporting a moisturized and supple-looking complexion
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Skin Texture: Aesthetic care focused on uneven or rough-looking skin
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Fine Lines: Addressing the appearance of superficial age-related lines
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Skin Elasticity: Supporting the appearance of firmer, more supple skin
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Skin Barrier Care: Complementing cosmetic treatments focused on skin conditioning
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Dull Complexion: Supporting a refreshed and more radiant appearance
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Uneven Skin Tone: Aesthetic care focused on the appearance of uneven complexion
These are cosmetic product-positioning claims rather than independently established clinical treatment outcomes.
Composition
Pure EXO Preparation – 50 mg
Stem Cell-Derived Exosome Preparation
The Pure EXO component contains extracellular vesicles described by JDBIO as derived from stem cells.
Exosomes are nanoscale extracellular vesicles released by cells. They can carry biological molecules and are studied for their involvement in cell-to-cell communication.
JDBIO publishes two distinct particle specifications:
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2 billion highly purified exosomes
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6 billion extracellular vesicle particles
These figures are manufacturer-associated claims, and their measurement methods have not been independently verified.
The 50 mg designation refers to the supplied Pure EXO preparation and does not establish the mass of purified exosomes.
Hyaluronic Acid Solution – 5 mL
Hyaluronic Acid (HA)
The accompanying HA solution provides a moisture-binding component within the EXO'ONE two-vial system.
Hyaluronic acid is widely used in skin-care formulations for its ability to attract and retain moisture, helping support the appearance of hydrated and supple skin.
The exact HA concentration and complete formulation have not been independently established.
Product Specifications
Product Name: EXO'ONE
Product Category: Exosome Skin Booster
Product Format: Two-Component Professional Aesthetic Preparation
Exosome Origin: Stem Cell-Derived
Published Purified Exosome Count: 2 Billion
Published Extracellular Vesicle Count: 6 Billion Particles
Pure EXO Component: 50 mg × 1 Vial
Hyaluronic Acid Component: 5 mL × 1 Vial
Packaging: 2 Vials per Box
Total Presentation: 1 Paired Set
Brand Company: JDBIO Co., Ltd.
Country of Origin: South Korea
Exosome & Hyaluronic Acid Formulation
EXO'ONE uses a two-component system that combines an exosome-containing preparation with a separate hyaluronic acid solution.
The exosome component is distinguished by its stem cell-derived extracellular vesicles, while the HA solution contributes moisture-binding properties associated with skin hydration.
Exosomes are an emerging area of scientific research because of their role in cellular communication. However, the biological properties of extracellular vesicles do not independently establish that a finished aesthetic product can regenerate tissue, prevent hair loss or deliver predictable clinical rejuvenation.
EXO'ONE is distinct from EXO'ONE V, a separate JDBIO formulation featuring ginseng-derived ingredients.
What's in the Box
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1 × EXO'ONE Pure EXO vial (50 mg)
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1 × EXO'ONE hyaluronic acid solution vial (5 mL)
Total: 2 Vials (1 Paired Set)
Storage & Handling
Store EXO'ONE according to the temperature and environmental conditions stated on the original manufacturer packaging.
Keep both components in their original sealed packaging until use. Protect the product from conditions that could compromise its stability.
Check the expiration date, batch number, and packaging integrity before use.
Preparation, permitted application methods, and handling after combining the components must follow the current manufacturer's instructions. The product's authorized administration route should not be assumed from its marketing description.
Professional Use Only
This product is intended for qualified medical or aesthetic professionals and is not intended for self-administration.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
Intended Use
This product should be used only for its intended purpose and in accordance with the manufacturer’s product information.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
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Frequently asked questions
How much can I save with Brunodermafiller?
Brunodermafiller is committed to offering you the most competitive prices. Depending on the products and quantities you purchase, you can save up to 20% compared to other distributors.
How to pay for your order?
Due to the high-risk classification of injectable aesthetic products, many standard payment providers do not support transactions for these products. As a result, we do not accept card payments, Apple Pay, or PayPal. All payments are made via bank transfer only.
Here’s how it works: Once you place your order, you’ll receive bank transfer details based on the currency you choose sent securely via email within 24 hours. Please check your spam, junk, or promotions folder if you don’t see it. If it’s still missing, feel free to contact our support team and we’ll resend it promptly.
Didn’t receive a payment instructions?
Payment instructions are sent via email within 24 hours of placing your order. If you haven’t received them, please check your spam, junk, or promotions folder—it’s often filtered there. Still nothing? Contact our support team and we’ll make sure you get them right away.
Are there any additional custom charges?
In rare cases, depending on your country’s customs regulations and current events, additional custom fees might apply at delivery. These are unfortunately outside of our control and vary by region. Most of our customers don’t encounter extra charges, but if it does happen, we just want you to be aware of them in advance. If you refuse to pay and reject delivery, no refunds will be issued. We’re always here to help if anything comes up.
Are there any additional transfer fees?
In some cases, certain banks may charge a small fee for international payments. While this isn’t something we control (and we never add fees ourselves), we don’t want you to feel that cost is coming out of your own pocket. It also isn’t the quickest or most convenient,and while it’s not ideal, we really appreciate you going through it. That’s why we offer you a small gift upon reaching checkout. You’ll get to choose from a selection of free products to thank you for your order and make sure you’re still getting full value. It’s our way of showing you that your effort doesn’t go unnoticed.
How long does the shipping take?
- USA, Canada, Japan: 2–5 business days
- Europe (excluding Germany and Italy): 3–5 business days
- Germany & Italy: 3–6 business days (tracking available after about 5 working days)
- South Africa: 7+ business days
- Dominican Republic: 8–12 business days
Average worldwide delivery time is 3–5 business days. Delays may occur due to customs clearance or flight schedules.
How is my order packaged?
For aesthetic treatment products such as injectables, we use temperature-controlled packaging when required, following strict safety and hygiene standards. All parcels are shipped in discreet packaging by default. No product names or medical terms appear on the outside of the box.
How to modify or cancel my order?
To modify or cancel your order, please contact us as soon as possible at info@brunodermalfiller.com.If your order hasn’t been processed or shipped yet, we’ll do our best to accommodate your request. Once it’s been dispatched, changes or cancellations are no longer possible, but you may be eligible for a return or exchange after delivery
The product packaging looks different. Is it authentic?
Yes, in many cases this is completely normal. Manufacturers may update their packaging, labels, security features, or product design without changing the product itself.
Packaging, logos, colours, security seals, QR codes, and labels may vary between production batches. If you have any concerns, please contact our support team with your order number and clear photos of the product and packaging.
Which saline or lidocaine should I use with this product?
Please follow the manufacturer's instructions for the specific product you have purchased. Preparation requirements vary between products and manufacturers.
Always refer to the manufacturer's official instructions supplied with the product. Products should only be prepared and administered by appropriately qualified healthcare professionals in accordance with applicable local regulations.