They deliver from Korea Worldwide, i live in Germany, they Sometimes faster then Deliveries from Germany, i dont know how they do it. They deliver high quality at best price. You dont get all of that anywhere else.
Nikola Kolobarić
ASCE+Derma Signal Kit
ASCE+ Derma Signal Kit is a professional exosome-based skin care system developed by ExoCoBio, South Korea, featuring plant-derived extracellular vesicles and a multi-ingredient skin-conditioning…
ASCE+ Derma Signal Kit is a professional exosome-based skin care system developed by ExoCoBio, South Korea, featuring plant-derived extracellular vesicles and a multi-ingredient skin-conditioning complex. Designed for skin revitalization, hydration and the appearance of visible signs of aging, it combines a lyophilized powder with a complementary liquid diluent.
The formulation features Rosa damascena callus extracellular vesicles, alongside peptides, amino acids, vitamins, coenzymes and hyaluronic acid. Its two-component presentation distinguishes ASCE+ Derma Signal from conventional single-formula skin boosters, bringing together exosome-related ingredients and a moisture-focused diluent.
Developed using ExoCoBio's proprietary ExoSCRT technology, the ASCE+ range reflects the company's specialized approach to extracellular vesicle isolation and purification. The documented Derma Signal SRLV presentation contains five paired sets, each consisting of 20 mg lyophilized powder and 5 mL diluent.
Key Features
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Plant-derived extracellular vesicles from Rosa damascena callus
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Proprietary ExoSCRT isolation and purification technology
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Two-component powder and diluent formulation
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Manufacturer-reported 5 billion exosomes per kit presentation
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Contains hyaluronic acid for hydration-focused skin care
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Includes peptides, amino acids, vitamins and coenzymes
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Developed for professional skin revitalization
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Focused on skin texture, hydration and radiance
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Marketed for the appearance of fine lines and wrinkles
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Five paired powder-and-diluent sets
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Developed by ExoCoBio, South Korea
Applications & Indications
ASCE+ Derma Signal Kit is marketed for professional aesthetic skin care focused on visible skin-quality concerns.
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Skin Hydration: Supporting a moisturized, supple-looking complexion
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Fine Lines and Wrinkles: Cosmetic care focused on the appearance of age-related facial lines
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Skin Texture: Supporting smoother, more refined-looking skin
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Skin Radiance: Aesthetic care focused on dullness and uneven-looking complexion
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Skin Elasticity: Supporting the appearance of supple, well-conditioned skin
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Skin Conditioning: Complementing professional aesthetic care focused on overall skin quality
The documented US product labeling describes external cosmetic use for wrinkle care and skin rejuvenation. It does not establish authorization for injection.
Composition
Rosa Damascena Callus Extracellular Vesicles
Plant-derived extracellular vesicles form a defining component of the ASCE+ Derma Signal formulation.
These vesicles are associated with Rosa damascena callus culture and are incorporated into the lyophilized powder.
Sodium Hyaluronate
Sodium hyaluronate, a form of hyaluronic acid, is included in the diluent and contributes moisture-binding properties to the formulation.
Peptide Complex
The published ingredient declaration includes several peptides, such as:
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Copper Tripeptide-1
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Acetyl Hexapeptide-8
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Palmitoyl Tripeptide-1
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Palmitoyl Tetrapeptide-7
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Palmitoyl Pentapeptide-4
These ingredients contribute to the formulation's cosmetic skin-conditioning profile.
Amino Acid Complex
The formulation contains amino acids including glycine, alanine, arginine, proline, serine and others.
Vitamins, Coenzymes and Antioxidant-Related Ingredients
The published composition also identifies ingredients including:
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Ascorbic Acid
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Retinol
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Glutathione
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Nicotinamide Adenine Dinucleotide
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Flavin Adenine Dinucleotide Disodium
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Thiamine Diphosphate
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Coenzyme A
The complete ingredient declaration is provided in the manufacturer's published product labeling.
Product Specifications
Product Name: ASCE+ Derma Signal Kit
Documented Product Variant: Derma Signal SRLV
Product Category: Exosome-Based Skin Care System
Primary Exosome-Related Ingredient: Rosa Damascena Callus Extracellular Vesicles
Technology: ExoSCRT
Formulation: Lyophilized Powder and Liquid Diluent
Powder Quantity: 20 mg per Set
Diluent Volume: 5 mL per Set
Packaging: 5 Paired Sets
Total Powder Quantity: 100 mg
Total Diluent Volume: 25 mL
Manufacturer-Reported Exosome Count: 5 Billion per Kit Presentation
Manufacturer: ExoCoBio Inc.
Country of Origin: South Korea
BDF SKU: BSB0044
ExoSCRT Technology & Formulation
ASCE+ Derma Signal Kit incorporates ExoCoBio's proprietary ExoSCRT technology, developed for extracellular vesicle isolation and purification.
Plant-Derived Extracellular Vesicles
The formulation features vesicles associated with Rosa damascena callus culture. These form the exosome-related component of the product.
Lyophilized Powder System
The powder component contains the extracellular vesicle ingredient alongside peptides, amino acids and other formulation components.
Hydrating Diluent
The accompanying liquid includes sodium hyaluronate and amino acids, complementing the powder's skin-conditioning ingredients.
Multi-Ingredient Skin Care
The combination of extracellular vesicles, peptides, amino acids and hydration-focused ingredients distinguishes ASCE+ Derma Signal Kit from conventional single-ingredient skin boosters.
The product is positioned for skin revitalization and the appearance of improved texture and radiance. Claims of guaranteed cellular regeneration, collagen production or therapeutic tissue repair require separate product-specific evidence.
What's in the Box
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5 × ASCE+ Derma Signal SRLV lyophilized powder vials (20 mg each)
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5 × ASCE+ Derma Signal SRLV diluent vials (5 mL each)
Total: 5 Paired Sets
Total Powder: 100 mg
Total Diluent: 25 mL
Storage & Handling
Store ASCE+ Derma Signal Kit at 2–8°C, according to the published US product labeling for Derma Signal SRLV.
Keep the product in its original packaging and protect it from unsuitable storage conditions.
Inspect the expiration date, batch information and packaging integrity before use.
The documented presentation is intended for external cosmetic use. Product handling should follow the current manufacturer instructions for the supplied market presentation.
Professional Use Only
This product is intended for qualified medical or aesthetic professionals and is not intended for self-administration.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
Intended Use
This product should be used only for its intended purpose and in accordance with the manufacturer’s product information.
Before Use
Always review the product packaging, labeling, and manufacturer information before use. Do not use if the product in the package is damaged or if product integrity is in question; contact us.
Regulatory Notice
Product requirements and permitted uses may vary by country. Buyers are responsible for ensuring compliance with applicable local regulations.
Disclaimer: Product information provided on this website is for general informational purposes only and does not constitute medical advice, treatment guidance, or instructions for use.
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Brunodermafiller is committed to offering you the most competitive prices. Depending on the products and quantities you purchase, you can save up to 20% compared to other distributors.
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How long does the shipping take?
- USA, Canada, Japan: 2–5 business days
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Average worldwide delivery time is 3–5 business days. Delays may occur due to customs clearance or flight schedules.
How is my order packaged?
For aesthetic treatment products such as injectables, we use temperature-controlled packaging when required, following strict safety and hygiene standards. All parcels are shipped in discreet packaging by default. No product names or medical terms appear on the outside of the box.
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To modify or cancel your order, please contact us as soon as possible at info@brunodermalfiller.com.If your order hasn’t been processed or shipped yet, we’ll do our best to accommodate your request. Once it’s been dispatched, changes or cancellations are no longer possible, but you may be eligible for a return or exchange after delivery
The product packaging looks different. Is it authentic?
Yes, in many cases this is completely normal. Manufacturers may update their packaging, labels, security features, or product design without changing the product itself.
Packaging, logos, colours, security seals, QR codes, and labels may vary between production batches. If you have any concerns, please contact our support team with your order number and clear photos of the product and packaging.
Which saline or lidocaine should I use with this product?
Please follow the manufacturer's instructions for the specific product you have purchased. Preparation requirements vary between products and manufacturers.
Always refer to the manufacturer's official instructions supplied with the product. Products should only be prepared and administered by appropriately qualified healthcare professionals in accordance with applicable local regulations.
