Overview
LIZTOX® 100 U is a premium cosmetic injectable containing highly purified Clostridium botulinum toxin type A. Manufactured by Huons Global Co., Ltd. (South Korea), it temporarily smooths dynamic facial wrinkles and prevents new lines from forming.
Composition
- Clostridium botulinum toxin type A: 100 U
- Human serum albumin: 0.5 mg
- Sodium chloride: 0.9 mg
Mechanism of Action
By blocking acetylcholine release at the neuromuscular junction, LIZTOX® induces localized muscle relaxation. This softens both fine and deep expression lines and inhibits the development of new wrinkles. When injected into sweat glands, it also reduces excessive perspiration without systemic effects.
Indications
Cosmetic
- Moderate to severe glabellar (frown) lines
- Forehead wrinkles and interbrow lines
- Crow’s feet
Therapeutic (off-label)
- Hyperhidrosis (palms, underarms)
- Benign blepharospasm
Efficacy
- Onset: 3–7 days
- Duration: 6–9 months
- Maintenance: 2–3 treatments per year
Preparation & Administration
- Reconstitution: Add sterile, preservative-free 0.9% saline. Gently swirl; avoid shaking.
- Use Window: Within 24 hours at 2–8 °C refrigeration.
- Injection: Intramuscular with a 30 G needle; dosing tailored to treatment area.
Storage
- Unopened vials: 2–8 °C (refrigerate)
- Shelf Life: 36 months from manufacture
Safety Profile
With 99.8% purity, LIZTOX® is well tolerated when administered by certified professionals. Common reactions include temporary injection-site discomfort and mild muscle weakness. Serious adverse events are rare and typically related to off-target diffusion. Always perform patient assessment and follow aseptic techniques.
