MEDITOXIN 200U

MEDITOXIN® 200U is a purified botulinum toxin type A formulation derived from Clostridium botulinum, developed by MedyTox Inc. Korea and approved by the Korean Drug Administration (KDA) in 2004. It is used for both aesthetic and therapeutic applications, functioning by blocking the release of acetylcholine at neuromuscular junctions, resulting in temporary, localized muscle relaxation.

MEDITOXIN is therapeutically comparable to Botox® (Allergan), but features minimal diffusion due to its high molecular weight, making it ideal for treating delicate facial areas such as the eyes and lips.

Indications and Uses

Aesthetic Applications:

• Forehead lines
• Glabellar lines (frown lines between eyebrows)
• Crow’s feet (periorbital wrinkles)
• Nasolabial folds
• Perioral lines (lip wrinkles)

Medical Applications:

• Hyperhidrosis (excessive sweating)
• Bruxism (teeth grinding)
• Chronic migraine
• Blepharospasm (involuntary eyelid spasms)
• Cervical dystonia (neck muscle contractions)

Mechanism of Action

MEDITOXIN® blocks acetylcholine transmission at the neuromuscular junction, causing temporary muscle relaxation. This smooths dynamic wrinkles and alleviates involuntary muscle activity.

Onset and Duration of Effect

• Onset of Action: 2 to 5 days
• Full Effect: 10 to 14 days
• Duration: Typically 4 to 6 months; up to 8 to 12 months in some patients

Target Application Areas

• Forehead
• Between the eyebrows (glabellar lines)
• Crow’s feet and periorbital area
• Nasolabial folds
• Lips and perioral region

Product Specifications

• Ingredients: Clostridium botulinum toxin type A, Sodium chloride (0.9 mg), Human serum albumin (0.5 mg)
• Packaging: 1 vial per box, 200 units per vial (lyophilized white powder)
• Appearance: Clear glass ampoule (may appear empty before reconstitution)
• Storage: -15°C to -5°C or refrigerated at 2°C to 8°C; protect from light; do not freeze after reconstitution

Recommended Treatment Guidelines

• Needle Size: 30G
• Reconstitution:
  • 200 units: dilute with 5 mL of sterile saline
  • 100 units: dilute with 2.5 mL of sterile saline
• Typical Dosage: Varies by indication; e.g., 20–30 units for glabellar lines

All procedures must be performed by a licensed healthcare professional trained in injectable techniques.

Side Effects and Precautions

When used correctly, MEDITOXIN® is generally well tolerated. However, side effects may occur:

Common Side Effects:

• Injection site pain or swelling
• Bruising
• Headache
• Temporary muscle weakness near the injection site

Rare but Serious Risks:

• Ptosis (eyelid drooping)
• Toxin spread to non-target muscles
• Allergic reactions

Patients should disclose medical history and medications prior to treatment. Use by unqualified individuals may lead to adverse effects such as facial muscle weakening.

Professional Use Only

MEDITOXIN® 200U is a prescription-only product intended exclusively for use by licensed medical professionals trained in aesthetic or therapeutic injection techniques.

By purchasing this product, you confirm that you are a qualified healthcare provider.